What is the half-existence of tapentadol?
None of the
metabolites add to the pain-relieving action. Tapentadol and its metabolites
are discharged solely (99%) by means of the kidneys. The absolute leeway after the intravenous organization is 1530 +/ - 177 ml/min. Terminal half-life is by and
large 5-6 hours after oral organization.
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